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New Offerings at ASAP BioPharma Conference Address Wide-ranging Impacts on the Healthcare and Life Sciences Industries

Posted By Cynthia B. Hanson, Saturday, August 27, 2016

As futuristic technologies become realities, professionals in the life sciences and healthcare industries are consulting their maps and charts to determine how their companies should navigate the new waters. Attendees at ASAP’s next BioPharma Conference will have an opportunity to collectively view the vast possibilities at “New Faces, Unexpected Places in Partnering: The Foresight to Lead, the Foundation to Succeed,” Sept. 7-9 at the Revere Hotel in Boston, Mass., USA. This year’s conference will address wide-ranging impacts on the industry, including the changing political scene, multi-partnering, the Internet of Things, and assistive technologies. 

 

After a rich offering of workshops on Sept. 7, the conference will kick off with a timely address from keynote speaker Dr. Sam Nussbaum, strategic consultant, EGB Advisors, Inc., who will present a talk on “Healing the U.S. Health Care System: Collaboration is Essential” (for more information about Nussbaum, see the link in this E-news), followed by a networking opportunity. The following two days include a plenary and about 26 forward-thinking, thought-provoking sessions from which to choose.

 

"The ASAP Biopharma Conference is a must-attend for alliance professionals of all experience levels,” says Jan Twombly, CSAP, former ASAP chairman of programming, and president of The Rhythm of Business. “It traditionally offers equal parts of looking outward to how the industry is changing and the implications for managing the risk and optimizing the value of alliances and other collaborations, as well as looking inward to develop the mindset, skillset, and toolset of a modern alliance capability.”

 

Well-known and respected industry luminaries are unveiling some never-before-presented information and perspectives. Take, for example, these insightful offerings:

  •  “Applying the Latest Alliance Management Research to Your Partnering Practice,” presented by Stuart Kliman, CA-AM, partner, alliance practice leader at Vantage Partners, and Shawn Wilson, DBA, vice president and general manager at Beaulieu Group: Two new groundbreaking research studies provide critical data on current trends, challenges, and opportunities in the alliance management profession.
  • “A New Model for Western and Chinese Pharmaceutical Partnering,” presented by Brent Harvey, CA-AM, director of Alliances, Eli Lilly and Company: "How To" insights on collaboration drawn from a longstanding, advanced partnership model between Eli Lilly and Company and WuXi AppTech, which provides, among other things, examples of how to leverage the regulatory environment in China to bring new drugs to market faster.
  • “New Partnerships between High Tech and BioPharma and the Alliance Management Practices to Support Them,” presented by Russ Buchanan, CSAP head of corporate alliances at Xerox Corporation, Joseph Schramm, VP strategic alliances at BeyondTrust, and David Thompson, CA-AM chief alliance officer at Eli Lilly and Company: Key insights provided by two highly accomplished technology company alliance executives that are sure to generate discussion about how biopharma alliance professionals can overcome potential challenges when partnering with tech companies.

 Preparing for rapid change is a central theme throughout the conference, and some of the workshops are offering essential “updates” for the alliance management toolbox. “With many more partners for many more purposes, new partnering models and differences to leverage, no alliance manager can rest on his or her laurels,” points out Twombly. “Unique among biopharma alliance management conferences, the ASAP Biopharma Conference leans in on where the profession is going, not where it has been."

 

Several workshops being offered emphasize the need to stay abreast of pressing industry changes, such as “Next Generation Alliance Management, Lean and Agile” facilitated by Lynda McDermott, CA-AM, president of EquiPro International, and Annick De Swaef, CSAP, managing partner of Consensa Consulting. Their workshop addresses digitalization’s influence on biopharma and cross-industry partnering, and it centers around basic questions that everyone in the industry is asking: “Are my team's current alliance best practices future proof? Should my alliance team acquire new skills?” De Swaef recommends combining ASAP’s newly launched in-company team training with the CA-AM Certification Exam Prep to strengthen company capabilities, expand into new areas of value creation, and introduce new best practices.

 

Twombly and Rhythm of Business Principal, Jeff Shuman, CSAP, are offering their own forward-thinking, 90-minute, hands-on workshop on design thinking for complex problems, such as for multi-partnering, non-asset-base alliances, and partnering with “sectors who run on much faster clock speeds than is typically seen in biopharma.” The data-driven, user experience-centered innovation and problem-solving methodology has been adapted for alliances and partnering practices.

 ASAP also plans to unveil a new custom-designed session: The ASAP Aquarium, facilitated by Twombly. Similar to a “fishbowl” communications activity, where the line is intentionally blurred between listeners and participants, ASAP’s version will start off with a deep discussion between industry thought leaders and senior-level partnering executives as the audience gazes into the aquarium. Listeners will then be able to “tap in,” join the discussion with a hot idea or new perspective, and replace the initial participants. The session provides for a fun way to actively engage and contribute to the collective wisdom of the group while exploring the questions that matter most as alliance professionals “engage with new faces and in unexpected places.”

Tags:  Alliance Professionals  Annick De Swaef  ASAP BioPharma Conference  BeyondTrust  Brent Harvey  collaboration  David Thompson  Dr. Sam Nussbaum  Eli Lilly and Company  EquiPro International  Jan Twombly  Jeff Shuman  Joseph Schramm  Lynda McDermott  Russ Buchanan  The Rhythm of Business  WuXi AppTech  Xerox 

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Managing Complex Software Engineering Alliances in a World Teeming With Digital Twins

Posted By Cynthia B. Hanson, Thursday, May 5, 2016
Updated: Wednesday, May 4, 2016

Michael Moser spends a good deal of his day collaborating in a digital world. With tech experience that reaches back 25 years with some of the biggest companies in the industry, such as HP, he is well-positioned to manage very complex software engineering alliances. When he came onboard at Dassault Systémes in Vélizy-Villacoublay, France, 15 years ago, he had already been introduced to interactive 3-D software, such as the engineering model for the Boeing 777. Since then, 3-D software has evolved significantly; it’s now a realistic, animated prototype capable of interconnecting via the cloud, he explained to me in an interview during the 2016 ASAP Global Alliance Summit “Partnering Everywhere: Expert Leadership for the Ecosystem,” held at the Gaylord National Resort & Convention Center, National Harbor, Maryland. For Moser, who offered the session “Master a Portfolio of Tactics to Animate the Partner Ecosystem,” the challenge of the day is deciding how to build partner networks that capture mushrooming opportunities in a growing industry. 

What are digital twins, and how do customers use them?
Dassault Systémes creates 3-D experiences for customers to sell a product. The customers can then present it digitally through simulation, which allows users to demonstrate and experience the product before a physical product is built. It’s called a digital twin, because you have a twin of your real-world product in the digital world. Dassault works with many industries, such as transportation, shipbuilding, aerospace and defense, high-tech products, architecture and engineering, consumer package goods (supermarkets), life sciences (the human body), energy creation and consumption, natural resources (mining), and security (panic patterns and fires).  The program can create digital twins for nature and the planet, such as altering a riverbed to impact a valley. It can simulate molecules and life and test chemical reactions. It’s all physics in the end. 

What types of projects have used a digital twin?
Electronics, data management, online connections, Internet of Things technology, sensors. It’s used by healthcare a lot, not only for analysis but also for emergency support, and security for simulating a terrorist attack or nuclear accident. If you apply this concept to a city, for example Singapore, which is one of our customers, it can be used to investigate the impact of changes on new buildings and physical parameters, such as lights, wind, and pollution. A client asked Dassault to simulate towing an iceberg from Antarctica to Africa for fresh water. It worked, so now they know it can be done. We also can build thermoanalytic systems for rising temperatures resulting from global warming that consist of human models walking through a city and experiencing temperature variation. 

What are the benefits of building digital twins?
It saves money for the customer as compared to the old model of build a prototype, such as a town in the desert. With a digital twin, you don’t have the expense of building or destroying a physical structure. It’s also much more green and sustainable because you don’t have to building physical structures. With a simulated car crash, you might need 10 prototypes for a crash. With a twin, you only have to build one to certify safety. Another benefit is flexibility: They can be altered to optimize the design. It also saves time. For example, instead of asking customers to walk aisles and document their findings on questionnaires, you can have customers wear goggles, send them through a store, and change the aisles based on capturing their reaction. With goggles, you are really in the midst of the digital twin because it scans the body, and you can actually see your hands. You look down at your feet, and your feet are in the virtual world. You also get better feedback because you can test multiple scenarios to optimize design and collect feedback to incorporate it. 

How do you try to capture this growing, and sometimes illusive, market?
Not only does Dassault simulate and construct prototypes, we are engaged in solution partnerships. There are an enormous number of technology partners with programs integrated into software. They develop solutions and want to sell them, but they aren’t always properly promoted. They need to sell to a broader ecosystem of customers and users. I take those partners’ positions and interests and design a support structure to sell and promote their solutions. One technique I use is a social marketing platform called “Talk,” an online community where partners can explain their solution to potential users. We integrate them to go to market, develop sales leads, and provide a platform to communicate akin to LinkedIn that is comprised of a Dassault customer base. 

What do you foresee for Dassault’s future?
The challenge is to bring it to next level and give more freedom to this ecosystem. If you have a bulletproof Pentagon style, you won’t meet the requirements of the new world, which is integrated instantly with apps. I am in favor of loose controls because if you don’t work that way these days, you will lose opportunity. These skills are more needed than deep technology skills, at least in the partnering environment—you need collaboration skills and open mindedness. 

Tags:  collaboration  Dassault Systémes  digital twin  ecosystem  go to market  Mike Moser  partnerships  technology partners  thermoanalytic systems 

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‘Recognizing Great Behavior’: Winners of 2016 ASAP Alliance Excellence Awards Receive Honors and Accolades for Innovative Problem-Solving at ASAP Global Alliance Summit

Posted By Cynthia Hanson, Thursday, March 3, 2016

“When we share and highlight best practices and learn from each other, part of the success worth recognizing is great behavior,” said Mike Leonetti, CSAP, ASAP president & CEO, emphatically as he presented the 2016 Alliance Excellence Awards during the awards ceremony at the ASAP Summit, “Partnering Everywhere: Expert Leadership for the Ecosystem,” at the Gaylord National Resort & Convention Center, National Harbor, Md. USA. In addition to the awards categories recognized in years past, ASAP introduced new honors at this year’s event.

 Warm applause turned into a standing ovation that swelled the room as Leonetti presented the new ASAP Guiding Light Award to Jan Twombly, CSAP, ASAP chairman of programming, for her exceptional and exemplary “good behavior,” leadership, and volunteerism. Leonetti noted that Twombly, president of The Rhythm of Business, for the past six years has invested literally hundreds of hours of time each year as a volunteer driving program development for the annual Summit as well as annual biopharma conferences for the past four years.  

 The new ASAP Chapter Excellence Award was awarded to the ASAP New England Chapter. Accepting the award was another ASAP luminary volunteer, Becky Lockwood, global board member and two-time president of the New England Chapter, for “going above and beyond alignment with ASAP’s vision. The New England Chapter continues to deliver excellence in everything they do for ASAP,” said Leonetti. In turn, Lockwood praised the suite of companies who have supported her efforts over the years, saying success would not have been possible without their volunteer time.

Leonetti then announced the winner of two ASAP Content Awards, first to Eli Lilly and Company and David Thompson, CA-AM, chief alliance officer, for their long history of devotion to ASAP from the early days of the association. Eli Lilly and Company's contributions include offering workshops, extensive volunteer time, and Lilly’s consistent editorial content in, and support of, Strategic Alliance Magazine. The second Content Award recognized Xerox and head of corporate alliances and ASAP chairman emeritus Russ Buchanan as well for countless hours of volunteer time “spreading the excellence we have been generating over the years,” and Buchanan’s colleague Candido Arreche, global director of portfolio & management for Xerox worldwide and a black belt in Six Sigma quality methodologies, for his dynamic ASAP workshop teaching style. 

The awards ceremony then announced and honored the finalists and recipients in multiple Alliance Excellence Award categories. 

The Alliance Program Excellence Award is presented to “organizations that have instilled the capability to consistently implement and manage alliance portfolios and demonstrated consistent success of those alliances over time.” This year’s award went to Bayer for its Alliance Capability Enhancement Project, now in its fourth year. The project was lauded for, among other things, its strong emphasis on collaborative capability and cultural development, deal-making and efficiency, new IT infrastructure, processes, and pilot programs. 

The goal was to “move the culture from an inward focus to a partnering mindset” commented Joseph Havrilla, senior vice president and global head of business development and licensing for Bayer Pharmaceuticals. This was accomplished through: 

  • Senior management engagement
  • Creating awareness within the organization and recognition and value of the importance of partnership, including pushing data out showing that a significant part of revenue came from partnership
  • Providing training to give people tools and techniques to manage partner conflicts and timelines

 National Instruments won the Innovative Best Alliance Practice Award, given to a company for “individual alliance management tools or processes that have made an immediate and powerful impact on the organization and/or the discipline of alliance management.” National Instruments received the award for outstanding achievement of a best practice with their innovative and highly accessible partner directory that allows customer to search across the partnering ecosystem and access in-depth profiles of partner capabilities, certifications, ratings, and reviews from partner customers. Implementation included the creation of more advanced search functions, markets, keywords, mapping, and other kinds of tools. As a result, the number of National Instruments partners grew very quickly from 600 to 1,000-plus over short time.

 This year’s Individual Alliance Excellence Award, which is presented for “excellence in planning, implementation, and results of a single alliance. … between two companies or multiple organizations,” went to International SOS and Control Risks. Their nearly seamless alliance has changed the way the market perceives support and assistance of business travelers and expats. Previously, Control Risk was doing pandemic planning, and SOS was doing security planning. The unique co-opetition through formation of a joint venture has resulted in significant benefits for both the companies and their clients in terms of crisis management, most recently during the Ebola crisis, Arab Spring concerns, and AcelorMittal Mining evacuation of 130-plus employees from Liberia.

 “The goal was to eliminate completely any competition, to merge and put them together into one. Obviously not an easy task by any stretch of the imagination,” said John Maltby, director, group strategy of alliances at Control Risks. “We took a year to design this alliance and structured it around distribution.” It works to completely eliminate the competition because “when it boils down, we are trying to operate safely in a difficult environment,” he added. “The alliance balances out quite complementary capabilities.”

 There were no submissions this year for the Alliance for Corporate Social Responsibility Award. The seven-member awards committee is chaired by Annlouise 

Tags:  alliances  ASAP Chapter Excellence Award  ASAP Content Awards  ASAP Guiding Light Award  Bayer  Becky Lockwood  Candido Arreche  collaboration  Control Risks  David Thompson  Eli Lilly & Company  International SOS  Jan Twombly  National Instruments  partner  professional development workshops  Russ Buchanan  The Rhythm of Business  Xerox 

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From Entrepreneur to Intrapreneur in the Healthcare Industry: Marcus Wilson’s ‘ASAP Quick Takes’ Tutorial at the 2016 ASAP Global Alliance Summit

Posted By Cynthia B. Hanson, Monday, February 22, 2016

ASAP is introducing an exciting new presentation format at the ASAP Global Alliance Summit March 1-4:  the “ASAP Quick Takes, patterned after “TED Talks” and well-received at the 2015 ASAP BioPharma Conference, will bring four provocative speakers to the stage to provide specific, complementary insights relating to emerging ecosystems. Organized around the theme “Partnering Everywhere: Expert Leadership for the Ecosystem,” the summit will be held just outside the US capital at the Gaylord National Resort & Convention Center, National Harbor, Maryland. Among the executives in the line-up is Marcus Wilson, president and co-founder of Anthem’s real-world research subsidiary, HealthCore. With reams of background information and perspective, Wilson is well-placed to speak on his topic “The Alliance Professional as Entrepreneur.” His experience as an entrepreneur has positioned him as a guiding force in his current mission to improve the safety, quality, and affordability of healthcare through data and research. He previously developed and ran the Health Outcomes and Clinical Research program for BCBS of Delaware, on which HealthCore is founded. 

ASAP Media: What are some techniques or approaches you use to jumpstart innovation and creativity as an intrapreneur? 

Marcus Wilson: Making the shift from an entrepreneur to working as an intrapreneur, I have found that there are two major concepts to embrace.  First, I advise intrapreneurs to have patience. Second, innovative concepts have to be well-socialized ahead of formal introduction. Each group or department impacted by that idea needs to be on board with the idea or subtle undermining will limit or completely inhibit progress. As we mature new concepts, we also put into our plan a “campaign” of sorts to help recruit key influencers across the enterprise. It is one step we take to pave the way for these new concepts to gain momentum. 

How is being an intrapreneur different than being an entrepreneur in your industry, and how do they accommodate alliance managers to set the stage for the next levels of meeting customer needs? 

I would imagine for some the difference is significant. Though we have dealt with significant adjustment issues over time, the conversion to being a part of a much larger organization has gone reasonably well. We sold our company to Anthem in 2003 because we felt strongly it was an important step in accomplishing our mission. They had the resources and the position within the healthcare system that would allow us to build capabilities and influence healthcare evidence development in a way we could not do as a small, independent company. Though we have certainly had our challenges, we have benefitted from a solid business structure within Anthem that preserved much of our “entrepreneurial” culture, which was well planned prior to our acquisition, and strong executive level support over the last 13 years. Our alliance managers have played, and continue to play, a key role in both our internal and external alliances. 

What kinds of changes do intrapreneurs need to make in the evolving healthcare ecosystem? 

The healthcare ecosystem can be quite complex, and I am convinced that alliance collaborations are going to be at the heart of solving some of its current issues. Ironically, I believe we can simplify the experience for the patient by collaborating across the ecosystem itself. Thus, intrapreneurial alliance managers will be collaborating in alliances of all kinds, often with multiple companies or institutions working on the same issue. I see this as a huge shift from where alliance management first began in life sciences, traditionally between partner companies of relatively equal size.  

How do you stay ahead of the curve in terms of innovation and "outside-in thinking?" 

A good entrepreneur knows that great ideas can come from literally anywhere. We need to champion this viewpoint as we work to innovate. Just this week, we were talking about the Top 10 trends in healthcare, and asking ourselves for each item: “How might this development influence our future business? How might we organize ourselves to better leverage that innovation? Are we in a unique position to bring that innovation to others?  As a novel, care research organization, what insights can we bring to a given issue?”  As this is core to our business, it is critical to maintain and harness that outside-in thinking 

How is HealthCore on the cutting-edge of intraprenuership and understanding customer needs in the evolving healthcare ecosystem? 

Our early years were spent embedded in a large group practice in Delaware. We worked to support better decision making between the physician and patient at the point of care. Many tough lessons learned in those formative years led us to begin developing innovative ways to get the right information to those two key decision makers. Since our inception in 1996, we have felt the best means of impacting patient outcomes was to influence the many decisions made prior to new drugs and technologies getting to the patient. Realizing the innovators (e.g., the pharmaceutical industry), the regulators (FDA in the US) and policymakers had a major impact on what eventually makes its way to the point of care, we positioned HealthCore squarely on the lines where healthcare stakeholders intersect. Our position gives us rare insight into the needs, priorities, and unique language of each of these stakeholders. In this effort, collaboration is key. We are owned by a payer and leverage the resources and raw materials (data and their important relationships with the providers and patients) from that payer to close critical gaps in evidence in collaboration with the industry and regulators, which facilitates better technologies getting to the market with the right evidence to support their effective use in patient care. It is often a very tough line to walk, and alliance management is essential to our success. 

Tags:  alliance management  alliances  Anthem  collaboration  data  emerging ecosystems  entrepreneur  healthcare  HealthCore  intrapreneur  life sciences  Marcus Wilson PharmD  outside-in thinking  pharmaceutical industry  policymakers  regulators  research 

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The Benefits of Sponsor and CRO Collaboration—from Leveraging Innovation to Sharing Patient Information

Posted By Cynthia B. Hanson, Saturday, October 17, 2015

For many years, Contract Research Organizations (CROs) have sought to move beyond their role as fee-for-service providers and branch out into strategic alliances with pharmaceutical companies. These emerging services alliances pattern to some degree the partnerships that pharmaceutical companies form with biotech firms and with each other—but there are differences too. This CRO/Sponsor evolution became a talking point on Thursday, Sept. 10 at the 2015 ASAP BioPharma Conference in the session “Enabling Innovation and Value Creation in Sponsor/CRO Collaborations.” Moderated by Doug Williams, business development consultant at BioDigital, the discussion addressed the benefits in two partnering mini-presentations: Covance/Eli Lilly and Company and EMD Serono/Quintiles.

 

In 2008, Lilly and Covance created a groundbreaking 10-year strategic agreement that spans the drug development process, explained Andrew Eibling, CSAP, global vice president and alliance manager at Covance, about the history of the partnership.  “It involved working across the spectrum and various silos of drug development.”

 

Today, Covance has a highly successful cardio vascular partnership with Lilly. At the beginning, it required lots of fine-tuning, because in the rush to get started, they missed out on some crucial steps, recalls Jay Turpen, senior director of clinical laboratory operations at Lilly.

 

“First, we got the right people together to frame out how we were going to work together. It’s so crucial to invest in defining the process: how to communicate, what hand-offs look like, handling escalation. There were skeptics from both companies, so we took time and invested in kaizan events to determine the likely areas where there was the most friction in the program, and invested proactively in those areas,” he added. “Creating a culture of one team with one approach and applying alliance management was successful, and we were able to enroll the study in less than … the scheduled 24 months, and it was 98-99 percent clean through the process.”

 

Then there was a second added valuepartnering on laboratory research. “What’s in the best interest of both Lilly and Covance as we build this new lab system? What information is in our mutual interest?” they asked. “We got literally thousands of people working on these alliances. There needed to be common linkages across those silos,” Turpen added. The central labs group started a unique rewards recognition program. And they reached the point where they now pass patient information back and forth.

 

The final results? “Lilly’s CEO said that it was the best study the company has ever done. It was a high five, a best practice, a solid metric for what a great job that team did,” said Eibling.

 

In the case of EMD Serono/Quintiles, Quintiles’ clinical development division wanted a CRO who got involved early in clinical stages sitting at the development table. The companies also were looking for processing standards, high benchmarks, and most of all, innovative minds at the boardroom table. They signed a partnership with EMD Serono in 2013, and the CRO became a partner in drug/biosimilar development.

 

“Clinical development is challenging because how do you persuade patients and physicians to join a trial? Or are you going to fall back on biosimilar drug development?” Those were some of the key questions raised by Raymond Huml, DVM, executive director of strategic drug development and head of global biosimilars strategic planning at Quintiles Biosimilars Center of Excellence, and Louk Pechtold, CA-AM, directoralliance management biosimilars, in the biosimilars unit at Merck Serono SA. 

 

Biosimilars are follow-on copies of originator medicines made from living tissues (e.g., monoclonal antibodies). The question of biosimilar drug development is increasingly important because by 2020, some $100 billion of original biological medicines will lose intellectual property protection.

 

They also addressed the question of how alliance managers factor into drug/biosimilar development. “We have upper management, middle level, and closer-to-the-ground alliance management. There are alliance managers that look over entire portfolios, but at the end of the day, you need someone who understands the differences or subtleties. And there are differences with biosimilars,” explained Pechtold.

 

“The main value in collaboration is leveraging innovation from one partner to another,” Huml added. Regulatory experience is a plus, and having a global reach can be an advantage. “Those with experience working with multiple companies also have an advantage over one-on-one,” he concluded.

Tags:  Alliance Management  Alliance Managers  alliances  biotech  Collaboration  Contract Research Organizations  Covance  CRO  drug/biosim  Eli Lilly and Company  intellectual property  Louk Pechtold  Merck Serono SA  pharmaceutical companies  Quintiles Biosimilars Center of Excellence  Raymond Huml  strategic alliances 

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