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Reset, Relaunch, Rebirth: Rejuvenating a Longtime Alliance to Create Future Value

Posted By Michael J. Burke, Thursday, October 17, 2019

What happens when a more than three-decade-old alliance that has gone through its share of turmoil nears the end of its contractual life? Does it simply wind down in collective exhaustion, ending with a whimper? Does it crash and burn? Or can it somehow rise from the ashes of the past?

            Two European biopharma companies struggled toward the answer to that question, and ended up resetting and relaunching their alliance to mutual benefit. Eric Ferrandis, CA-AM, vice president of strategic alliances at Ipsen, and Fabrice Paradies, director of industrial business development and global commercial alliance at Debiopharm Group, described the process of bringing their two companies’ productive partnership back from the brink and back to life in their presentation, “Partnership Reset and Launch: How to Complete the Past?” at the recently concluded ASAP BioPharma Conference 2019, held Sept. 23–25 in Boston.

            Paris-based Ipsen, a 90-year-old company specializing in oncology, neuroscience, and rare diseases, and the 40-year-old Debiopharm, a drug development company based in Lausanne, Switzerland, had an alliance going back to 1983 that had been very productive for both of them. This 35-year partnership sprang from a series of agreements and amendments for the licensing of Triptorelin—brand name Decapeptyl—a drug used in the treatment of advanced prostate cancer, endometriosis, and breast cancer, among other conditions.

            The DKP alliance, as it was known, created value for both companies, but as Ferrandis and Paradies acknowledged, it also had been set up in such a way as to cause “pain points” that those working on the alliance had never been able to address holistically. So what to do?

            As the alliance agreement neared its end by mid-2018, both companies’ CEOs agreed that a new alliance framework must be put in place, with negotiation leads empowered to get a new contract signed by the end of that year and relaunch the alliance for the long term. Accordingly, by July 2018 the companies hired the consultancy The Rhythm of Business to help get their partnership back on track by identifying the key problems that had hindered its efficient functioning and to assist in rebuilding a common vision for the alliance.

            The initiation of the reset process involved two workshop sessions covering two days and involving personnel from key functions across both companies. Among the key findings that emerged from those sessions:

  • Both Ipsen and Debiopharm still saw a promising future for the DKP alliance.
  • They also felt that the alliance’s current economic model would not unleash the full growth potential of the brand.
  • More indications launched in more territories globally would deliver greater value to both partners.
  •   Greater proactive investment in product innovation and life cycle management was required for continued success and growth.
  • The long-term relationship had laid a solid foundation, but some deep-seated divisions and differences still needed to be overcome.

Armed with these findings, the two companies’ negotiation teams—primarily three people on each side, with support from above and below—set about to restructure the alliance and set it on a better course, by:

  • Aligning financial terms in the new economic model, across all formulations of the product
  • Developing a joint life cycle management plan that fuels appropriate product innovation
  • Strengthen alliance governance to support the more ambitious economic model and operating framework
  • Working hard to build trust and ensure transparent and effective communication

As Ferrandis commented, “Everything is about trust.”

            As the new agreement was being negotiated, it was agreed that the old contract would remain in effect and the status quo of the alliance would continue on both sides. Other key points, according to Ferrandis and Paradies:

  • The need for a reset was agreed on by both companies.
  • There was buy-in by both companies’ senior leaders and leadership teams.
  • The revenue from the DKP alliance was important to both companies, so it was clearly understood that the reset/relaunch effort needed to go deep into both organizations.
  • The negotiation teams included representatives from alliance management, business development, and legal, and had input from a number of other functional areas—as well as critical support from senior leaders.

Both Ferrandis and Paradies admitted that while everyone involved wanted to “move fast” on the reset effort, it was important to lay the groundwork even before negotiations commenced to get the partnership relaunched. “We had to change the mindset” internally, said Paradies. Doing this work ahead of time—and having “the right people in the room,” as Jan Twombly, CSAP, principal of The Rhythm of Business, noted—led to a “new partnership spirit” in the alliance, according to Ferrandis.

            Ferrandis also cited leadership as “the greatest alliance management skill,” adding that behaving as a leader includes going to senior leadership when necessary to get buy-in and help get issues resolved.

            A new agreement was signed in 2018 that provided for 15 additional years of partnership between Ipsen and Debiopharm, featuring a new economic model with better-aligned financial terms, a new R&D framework with cost sharing for codevelopment mechanisms, new governance giving Ipsen final say over development and commercialization and Debiopharm control over manufacturing, and what the copresenters called a “commercial bold ambition.”

And once the new contract was signed, senior company personnel celebrated with a joint dinner in Montreux, Switzerland, on Lac Léman (Lake Geneva). The moral? For the rebirth of a long-running alliance like this one, said Ferrandis, “Don’t forget to celebrate each time you can.”  

Tags:  alignment  alliance management  codevelopmen  Debiopharm Group  Eric Ferrandis  Fabrice Paradies  Ipsen  negotiation  partner  partnership  Partnership Reset ASAP BioPharma Conference  R&D 

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ASAP and WorkSpan Announce a Partnership to Strengthen Their Collaboration and Grow the Ecosystem Community

Posted By Kimberly Miller, Monday, September 30, 2019
Updated: Monday, September 30, 2019

WorkSpan and the Association of Strategic Alliance Professionals (ASAP), two organizations that are deeply engaged with alliance and ecosystem professionals, are proud to announce a new partnership designed to grow and enhance both organizations’ abilities to deliver world-class services to these communities.

WorkSpan is the category leader for Ecosystem Cloud where alliance, channel, and ecosystem leaders connect, co-create, co-market, co-sell, measure, and scale with their ecosystem partners in a single, secure network to grow business together.  ASAP is the only nonprofit, professional association and community which certifies and is dedicated to elevating and promoting the profession of alliance, partnerships, and ecosystems management. 

Over recent years, ASAP and WorkSpan have collaborated on a number of engagements, joint marketing activities, event sponsorships, and joint communications.  

In order to strengthen and deepen that collaboration, today the organizations announce a new partnership, working together on a number of dimensions with the intention of delivering greater service to our shared communities of alliance and ecosystem professionals.

The partnership covers a number of strategic programs in five primary dimensions including:

  • Global and local chapter events
  • Training and certifications(strategic-alliances.org)
  • Online community (AllianceAces.com)
  • Content around alliances and ecosystems
  • Alliance and ecosystems best practices

Through this partnership, WorkSpan and ASAP see the opportunity to strengthen each organizations’ mission and provide greater opportunities for ASAP to deliver high-quality resources to alliance professionals and grow to support additional programs in the future.

 

“ASAP and WorkSpan are ideal partners that support ASAP’s goals to develop, educate, and grow its community of practitioners, in addition to helping them identify the best processes andpractices to manage their partnerships and ecosystems successfully,” said Mike Leonetti, president and CEO of the Association of Strategic Alliance Professionals.

 

“We’ve always had the highest regard for ASAP as a professional association and have enjoyed collaborating with Mike and the ASAP Board over the years.  We look forward to a strong partnership that will deliver immediate benefits to the alliance and ecosystem professionals’ community.”  said Amit Sinha, co-founder and chief customer officer, WorkSpan.

 

The partnership is managed by WorkSpan’s Vice President of Marketing, Chip Rodgers and Mike Leonetti of ASAP. As part of the agreement, Mike Leonetti will join the Alliance Aces community board and Greg Fox, WorkSpan general manager for the communications & networking industry, will join the ASAP advisory board.

 

About ASAP

The Association of Strategic Alliance Professionals (ASAP) is the only professional association dedicated to elevating and promoting the profession of alliance, partnerships, and ecosystems management. Founded in 1998, the organization provides professional development, networking, and resources for cultivating the skills and toolsets needed to manage successful business partnerships. ASAP’s professional certifications include the Certificate of Achievement-Alliance Management (CA-AM) and Certified Strategic Alliance Professional (CSAP).  Find out more about key ASAP events, webinars, and other content at http://www.strategic-alliances.org.

 

Link to the announcement by WorkSpan 

About WorkSpan

WorkSpan is the Category Leader for Ecosystem Cloud.  With Ecosystem Cloud, our customers are capturing a disproportionate share of the Ecosystem Economy — and you can too.  Join the WorkSpan network where alliance, channel, and ecosystem leaders connect, co-create, co-market, co-sell, measure, and scale with their ecosystem partners in a single, secure network to grow business together.

 

WorkSpan is a privately held company backed by Mayfield and is growing its network of global enterprise customers including SAP, Cisco, Microsoft, Accenture, Google, SAS, VMware, NetApp, Nutanix, NTT Data, Lenovo, and others.

Tags:  alliance  Amit Sinha  collaboration  ecosystem  partnership  strategic programs  WorkSpan 

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The Living Heart Project: Insights from a Global Collaboration

Posted By John M DeWitt, Wednesday, March 13, 2019

“If We Work Together, Can We Build a Human Heart?” This was the tagline for Steve Levine’s March 12 Leadership Spotlight session at the 2019 ASAP Global Alliance Summit. His captivating presentation detailed, in TED Talk style, his multi-year journey as a collaboration leader to find the answer to this question. (Spoiler alert: The answer is yes.)

Levine is the senior director of life sciences at Dassault Systèmes, as well as the founder and executive director of the Living Heart Project. He holds a PhD in materials engineering from Rutgers University, and in 2015 was elected as a Fellow in the American Institute for Medical and Biological Engineering.

Levine opened his presentation by describing his current company, the 40-year-old Dassault Systèmes, a computer-aided design company that evolved to offer a “3D experience” software platform used by many industries and the public sector. Most cars on the road today, Levine said, are designed by Dassault software, which renders three-dimensional experience with visually as well as technically exact realism. Car manufacturers use Dassault simulation technology to not only design cars, but to crash test them as well. For example, BMW, a Dassault customer, stopped physically crash-testing cars in 2013.

Also in 2013, Levine began to explore the idea of building a virtual human heart, one that could be used to diagnose ailments and educate people about the organ. Even in the big data era, this was a truly enormous task, given the amount of detail that he and his team needed to fit in. They needed new models for tissue, fiber orientations, coupled multiphysics (the electrical impulses that control the heart muscle), valves, and hemodynamics (flow of blood through the heart), among other things.

The medical community already has the understanding of the heart necessary to build a digital one, but that knowledge is “deconstructed,” as Levine says, distributed around the globe in many minds and texts and databases. The single greatest challenge, then, was getting all of that knowledge into one spot, then applying it. Or, as Levine asked the audience, once the pieces are gathered, “Can we put it back together?”

In order to put the heart back together, Levine needed to bring together many of the best medical and engineering minds from around the world (his team had members from 24 different countries) in order to pool their knowledge and capabilities. To accomplish this, while protecting what most partners would consider their proprietary intellectual property, he designed a hub-and-spoke collaboration, with Dassault Systèmes at the center. By centralizing trust, he maximized the amount of information exchanged. Not surprisingly, as trust in the Dassault hub grew, the spokes became increasingly comfortable and increasingly open with sharing their knowledge to support the common mission.

In the end, this Herculean feat of collaboration allowed Levine and his team to launch a completed and realistically rendered digital heart into the cloud in 2015. This digital model is expected to pave the way for personalized heart models, used to determine more exact treatments, safer and faster tests for drugs, image diagnostics, and, one day, for this technology to be applied to a patient’s entire body. Doctors and pharmacists would then be able to better design a specific treatment for the patient in question, with no guesswork involved—because the treatment can be tested on the virtual model before given to the real human.

To learn more about Steve Levine and the Living Heart Project, visit www.3ds.com/heart. Stay tuned to the ASAP blog and Strategic Alliance publications for the ASAP Media team’s comprehensive coverage of the 2019 ASAP Global Alliance Summit.  

Tags:  3D experience  ASAP Global Alliance Summit  collaboration  Dassault Systèmes  life sciences  partners  partnership  Steve Levine  The Living Heart Project 

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The Virtuous Cycle in Alliance Management—a Summit Spotlight Exclusive (Part 2)

Posted By Cynthia B. Hanson, Tuesday, March 5, 2019
Updated: Monday, March 4, 2019

“The alliance manager’s role is to understand the importance of timing,” advises Christine Carberry, CSAP, in Part One of ASAP Media’s interview with the seasoned alliance manager and former chief operating officer of Keryx Biopharmaceuticals (now a subsidiary of Akebia Therapeutics). Carberry, who also previously served as chair of the ASAP board of directors, will be providing a leadership spotlight plenary session, “Collaborate-Create: The Value of the Virtuous Cycle,” at the 2019 ASAP Global Alliance Summit, “Agile Partnering in Today’s Collaborative Ecosystem,” March 10-13 at the Westin Fort Lauderdale Beach Resort in Fort Lauderdale, Florida. ASAP Media’s conversation with Carberry continues below.

Carberry’s role for six months of her year working for Keryx was as co-leader of integration planning with counterpart Akebia. Early on, she realized that her role wouldn’t continue with the new organization. She is philosophical about it. “You are working on trying to have everybody see the value of the merger—employees in the companies, investors, and shareholders. Yet people know you are not going to be part of it,” she explains of the challenge. “It’s about taking the time, if you can, to explore and not think that you have to jump right back into doing exactly what you were doing. Each experience leads to another.”

Alliance mangers are seekers of “the high road” trying to rise above conflict and egos, and keeping everyone focused on the common goal.  “You’re really a navigator,” she adds. “One of the criticisms that we’ve heard is alliance managers need to think of themselves much more broadly. And think of themselves as the people always looking for a portfolio of alliances and expanding value, not just be within the confines of agreements that you have today. That’s the challenge I want to give to the audience [at the Summit] in thinking about how we can have a greater impact by making better, stronger connections between ideas and resources, creating better conditions for collaboration. Your alliance portfolio is dynamic, and I think that alliance managers can create more value by really understanding that one alliance is one piece of a company portfolio and needs to align with company strategy.”

Before her one-year stint with Keryx, Carberry spent three and a half years with FORUM Pharmaceuticals (formerly EnVivo Pharmaceuticals) and 26 years with Biogen, where she stated out in an entry-level position during a time when genetic engineering was “scary science.” Biogen was a Fortune 500 international company that brought several drugs to patients “that changed their lives,” she adds. 

Despite being in transition between jobs, Carberry has “a very full plate.” In addition to her spotlight plenary session, as chairman emerita of ASAP, she will attend the Summit board and advisory meetings and will lead a roundtable about alliance management in a crisis situation. “It’s similar to what I’ve done in other transitional periods. It allows me to increase involvement in leadership roles,” she says.

Learn about Carberry’s talk and other leadership sessions and register for the 2019 ASAP Global Alliance Summit at http://asapsummit.org. See the ASAP Media team’s comprehensive before, during, and after coverage of the 2019 Summit in Strategic Alliance publications and on the ASAP blog.  

Tags:  Akebia Therapeutics  Alliance Excellence Award  alliance manager  Christine Carberry  conflict  digital  expanding value  Keryx Biopharmaceuticals  partnership  Patheon  strategic partner  technology  Thermo Fisher 

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The Virtuous Cycle in Alliance Management—a Summit Spotlight Exclusive (Part 1)

Posted By Cynthia B. Hanson, Tuesday, March 5, 2019
Updated: Monday, March 4, 2019

“There is a time and purpose for everything. So the alliance manager’s role is to understand the importance of timing.” Thus advises Christine Carberry, CSAP, a seasoned alliance manager and former chief operating officer of Keryx Biopharmaceuticals (now a subsidiary of Akebia Therapeutics). Carberry, who also previously served as chair of the ASAP board of directors, will be providing a leadership spotlight session “Collaborate-Create: The Value of the Virtuous Cycle” at the 2019 ASAP Global Alliance Summit, “Agile Partnering in Today’s Collaborative Ecosystem,” March 10-13 at the Westin Fort Lauderdale Beach Resort in Fort Lauderdale, Florida.

A virtuous cycle connects right ideas with right resources in the right timing, she continues. “Timing is part of creating the right environment for collaboration and pulling those pieces together and then generating value,” Carberry explains. “That value often generates new ideas that just feed back into it. Growing new ideas may mean you need different kinds of resources. You may have an idea on how to improve a patient’s experience in a clinical trial. From that, you may come up with an idea that there’s a way to make that experience better using technology. Now you need different resources and skillsets to improve the patient experience in a digital way.”

Carberry’s talk is based on 30 years of management experience. Right now, she is between companies after Keryx Biopharmaceuticals and Akebia Therapeutics merged in December. The two companies are under consideration for a 2019 ASAP Alliance Excellence Award for their handling of a supply disruption where patients could not obtain a jointly manufactured drug. Access resumed after the companies teamed togetherfrom the C-level to the operational teamsto create a quick, viable solution.  

 

 “We had to navigate this partnership when Patheon merged with Fisher, and Keryx with Akebia,” Carberry explains. “Traditionally, biopharma companies treat CMOs as vendors, not as collaborators. … Applying all of the ASAP approaches and tools to the CMO I think creates a much stronger partnership, and it was demonstrated in this supply disruption situation. We needed high levels of trust with CEO engagement. It wasn’t business as usual. It was requiring people to go above and beyond,” she continues. “Agile is a good word for it. That willingness to be flexible and agile is less likely to happen if you are treating your CMO as a vendor rather than as strategic partner. “

 

See the ASAP Blog for Part Two of this interview with Christine Carberry, CSAP. Learn about Carberry’s plenary talk and other leadership sessions at the 2019 ASAP Global Alliance Summit, and register for the event, at http://asapsummit.org. See the ASAP Media team’s comprehensive before, during, and after coverage of the 2019 Summit in Strategic Alliance publications and on the ASAP blog.  

Tags:  Akebia Therapeutics  Alliance Excellence Award  alliance manager  Christine Carberry  digital  Keryx Biopharmaceuticals  partnership  Patheon  strategic partner  technology  Thermo Fisher 

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